By Justin Melvin

The puzzle is presented as a series of groups of mini-puzzles. Each group can be solved using techniques from one of the headings in the ACME Have You Tried document:

What is it? (3)

• …Braille: `THE LETTER AITCH` (`H`)
• …using the Library of Congress system: `THE SCARLET LETTER` (`A`)
• …getting on the T: Draw lines connecting the three stations to form a letter (`V`)

Letters and words (14)

• …determining if it is a Rot 13: `THE BEGINNING OF ETERNITY AND THE END OF TIME` (`E`)
• …rearranging the letters (“anagramming”): `THE LETTER THAT PRECEEDS ZED` (`Y`)
• …looking at a computer keyboard: The letters form a circle around a letter (`O`)

Numbers (1)

• …treating numbers as latitude/longitude: Draw lines between the coordinates to form a letter (`U`)
• …matching numbers to MIT buildings: The three named buildings form the shape of a lettter (`T`)
• …treating numbers as radio stations: The call signs for the stations all end in the same letter (`R`)

Thirteen ways of looking at a puzzle (10)

• …connecting the dots: `THE LETTER BETWEEN J AND H` (`I`)
• …looking at it in a mirror: `THIS ONE IS THE LETTER E` (`E`)
• …saying it out loud to someone else: `I’LL SAY THAT YOU WANT TO TAKE D AS THE NEXT ONE` (`D`)

Numbers (2)

• …seeing if prime numbers are involved: The 20th prime number (71) is missing (`T`)
• …treating numbers as ASCII numbers: `ONE OUGHT OBTAIN ONE OH` (`O`)
• …graphing it parametrically: Graphs a circle above a rectangle, for a lowercase letter (`I`)

For starters (4)

• …typing it into a search engine: The first hit from Googling these words is `“The Letter N Song”` (`N`)
• …reading the title and the blurb: The puzzle’s blurb says how to interpret a double asterisk (`D`)
• …pursuing a train of thought: The missing railroad from Monopoly is `READING RAILROAD` (`E`)

Zen (2)

• …asking for fresh brains: The victim is dead, so the eyes are crossed out (`X`)
• …thinking about what’s missing: One letter is missing from the pangram (`I`)
• …trusting someone else’s instincts: (`N`)

Thirteen ways of looking at a puzzle (10)

• …tilting it: Looking from the edge of the screen, it says `TANGO` (`T`)
• …folding it: Fold the light lines together so they touch; it says `THE LETTER YOU SHOULD USE IS INDIA` (`I`)
• …looking at it upside down: The text clues `TEA` (`T`)

Numbers (3)

• …treating numbers as atomic weights: Drawing a line between the elements on the periodic table forms the shape of a letter (`L`)
• …seeing if fundamental constants are involved: This is Euler’s constant (`E`)
• …using it as a phone number: On a phone, these form the shape of a letter (`S`)

Once all of the mini-puzzles have been answered, the extracted letters read `HAVE YOU TRIED TO INDEX IN TITLES`. Using the numbers in each section of the puzzle to index into the corresponding section of the Have You Tried document:

Section Index Letter
`WHAT IS IT`3`A`
`LETTERS AND WORDS`14`D`
`NUMBERS`1`N`
`THIRTEEN WAYS OF LOOKING AT A PUZZLE`10`A`
`NUMBERS`2`U`
`FOR STARTERS`4`S`
`ZEN`2`E`
`THIRTEEN WAYS OF LOOKING AT A PUZZLE`24`A`
`NUMBERS`3`M`

Reading in order yields the answer, `AD NAUSEAM`.