One of the logical things to try with a bunch of integers is to factor them. Do this, and one will observe that there are no factors over 90, and a surprisingly large number greater than 65. In fact, each integer is the product of a set of (not necessarily prime) factors in the range 65–90. Given the title, these ought to be interpreted as ASCII capital letters.
In particular, each integer is the product of the ASCII letters in a particular word (occasionally some knowledge of English is required to disambiguate). In the given order, these words are:
FORTY YEARS BEFORE LAST NOVEMBER FIRST AT EIGHT TWENTY AND TWENTY FOUR SECONDS ZULU POSIX TIME
In POSIX time (seconds since midnight Jan 1 1970), that is represented by the integer 26295624.
Repeating the process gives the letters in the answer ECHO.